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 Top News    

Smoking More Than Five Cigarettes A Day Provokes Migraine Attacks
Tobacco acts as a precipitating factor for headaches, specifically migraines. This is indicated in a study which shows that smokers have more migraine attacks and that smoking more than five cigarettes a day triggers this headache. The work has appeared in The Journal of Headache and Pain. The influence of tobacco as a precipitating, non-causal factor of migraine attacks has produced contradictory data in scientific literature.

Migraines More Prevalent In Women
Headaches are a widespread problem in the United States, affecting roughly 45 million people. Migraine headaches affect millions of Americans each year they are the most common type of headache that sends patients running to their doctor's office. Migraines occur when constricting blood vessels in the brain cause intense, recurring vascular headaches. Like other forms of headaches, women suffer from migraines more frequently than men.

Smoking More Than 5 Cigarettes A Day Provokes Migraine Attacks
Tobacco acts as a precipitating factor for headaches, specifically migraines. This is indicated in a study which shows that smokers have more migraine attacks and that smoking more than five cigarettes a day triggers this headache. The work has appeared in the Journal of Headache and Pain. The influence of tobacco as a precipitating, non-causal factor of migraine attacks has produced contradictory data in scientific literature.

Migraine And Increased Risk Of Cardiovascular Disease: Migraine Frequency Plays A Role
Women who have migraines with aura may be more likely to have a stroke or heart attack than women who don't have the condition, and the association varies by migraine frequency, according to research published in the June 24, 2009, online issue of Neurology®, the medical journal of the American Academy of Neurology. An aura is a visual or other sensory disturbance that occurs before the migraine starts, such as seeing bright lights.

Migraines With Aura In Midlife Associated With Increased Prevalence Of Brain Lesions In Older Age
Middle-aged women who had migraine headaches with aura (sensory disturbances, such as with vision, balance or speech) had a higher prevalence of brain lesions when they were older, compared to individuals without similar types of headaches, according to a study in the June 24 issue of JAMA. Migraine is a common neurovascular disorder that affects approximately 11 percent of adults and is more common in women than men.

Migraines With Aura In Middle Age May Be Associated With Late Life Brain Lesions
Women who suffer from migraine headaches in middle age particularly those accompanied by neurological aura are more likely to have damage to brain tissue in the cerebellum later in life, according to a study by researchers at the Uniformed Services University of the Health Sciences, the National Institute on Aging (NIA) of the National Institutes of Health (NIH) and the Icelandic Heart Association in Reykjavik.

FDA Approves Cambia™ For Migraine
Kowa Pharmaceuticals America, Inc. (KPA), a privately-held specialty pharmaceutical company headquartered in Montgomery, AL, announced today that the U.S. Food and Drug Administration (FDA) has approved Cambia™, a diclofenac-based non-steroidal anti-inflammatory drug ("NSAID") combined with potassium bicarbonate, for the treatment of acute migraine with or without aura in adults.

Midlife Migraine With Aura Linked To Brain Lesions In Later Life
An international team of researchers found that middle-aged women who had migraines with aura (perceptual disturbance that may precede or accompany the migraine such as a strange light or smell, or disturbed balance or speech) were more likely to develop brain lesions when they were older compared to counterparts who did not have such headaches.

Migraines, Pregnancy And Stroke
For many women who suffer from migraines, pregnancy can be a period of relief from their headaches. Studies have found that preexisting migraines diminish or disappear in 42% to 98% of pregnant women. However, new, persistent, or worsening migraines during pregnancy can signal a serious problem that could result in a stroke.

Astronauts' Survey Suggests New Space Headache Category
Researchers are calling for space headache to be established as a new secondary disorder after carrying out a study of 17 astronauts, published in the June issue of Cephalalgia. Their study jettisons the theory that astronauts' headaches are normally caused by space motion sickness, after showing that more than three-quarters of those studied had no connection.

SUPERVALU PHARMACIES Aids Migraine Sufferers For A Cause
Summer isn't any fun when you have a headache. But for many of the 30 million Americans who suffer from migraine headaches, solutions for soothing headache symptoms may be just around the corner.

MAP Pharmaceuticals Phase 3 Trial Of Levadex™ Migraine Product Candidate Meets All Four Primary Endpoints
MAP Pharmaceuticals, Inc. (Nasdaq: MAPP) announced that the efficacy portion of its first Phase 3 clinical trial evaluating its novel LEVADEX™ orally inhaled migraine therapy met all four primary endpoints. Additional endpoints showed that LEVADEX provided rapid and sustained pain relief for up to 48 hours after dosing.

Common Migraine Pain Condition Also Prevalent In Cluster Headache
A pain condition common in people with migraines also has a high prevalence in patients with cluster headache, according to a study conducted by researchers at the Jefferson Headache Center at Jefferson Hospital for Neuroscience. Approximately half of a group of patients with cluster headaches experienced cutaneous allodynia, a condition that causes patients to have pain as a response to normally inconspicuous sensations, according to Michael Marmura, M.D.

The Evolution Of Migraine From Episodic Headache To Chronic Disorder
Patients living with migraine have strong reason for new optimism concerning a positive future. Two review articles and an accompanying editorial, "The Future of Migraine: Beyond Just Another Pill," in the current issue of Mayo Clinic Proceedings, are the basis for an ironic premise. "Migraine is a potentially chronic, progressive disease that substantially affects patients, families, workplaces, and society," according to the editorial written by Roger Cady, M.D.

MAP Pharmaceuticals Phase 3 Trial Of LEVADEX(TM) Migraine Product Candidate Meets All Four Primary Endpoints
MAP Pharmaceuticals, Inc. (Nasdaq: MAPP) announced that the efficacy portion of its first Phase 3 clinical trial evaluating its novel LEVADEX(TM) orally inhaled migraine therapy met all four primary endpoints. Additional endpoints showed that LEVADEX provided rapid and sustained pain relief for up to 48 hours after dosing.

Magnets For Migraines
New animal research suggests that a noninvasive therapy called transcranial magnetic stimulation (TMS) may help treat chronic migraines. During TMS, the electrical activity in the brain is influenced by a pulsed magnetic field generated through coils of wire. The wires are wrapped in plastic and held close to the scalp. The location of the device allows for stimulation of specific areas of the brain.

Study Examines Novel PFO Closure System
A new device designed to close a common heart defect known as a patent foramen ovale (PFO) is safe and effective at 90-days follow up, according to a new study released at the Society for Cardiovascular Angiography and Interventions (SCAI) 32nd Annual Scientific Sessions in Las Vegas. PFO is a common condition in which a hole that connects the two upper chambers of the heart (atria) during fetal development fails to close properly after birth.

Caffeine Withdrawal Examined
Ever miss your daily cup of coffee and subsequently get a pounding headache? According to reports from consumers of coffee and other caffeinated products, caffeine withdrawal is often characterized by a headache, fatigue, feeling less alert, less energetic and experiencing difficulty concentrating. Stacey Sigmon, Ph.D.

Neuralieve Announces New Data On The Use Of Transcranial Magnetic Stimulation (TMS) For The Treatment Of Migraine Aura
Neuralieve, a medical technology company pioneering a new approach to treat migraine headache, reported positive data on the mechanism of action of TMS technology for the treatment of migraine aura. The results will be presented during the annual American Academy of Neurology (AAN) Scientific Meeting in Seattle by Peter J. Goadsby, MD, PhD, Professor and Director of the Headache Program at the University of California, San Francisco.

Promise For Non-Drug Treatment Of Migraine From New Therapy Based On Magnetic Stimulation
IA new UCSF study examining the mechanism of a novel therapy that uses magnetic pulses to treat chronic migraine sufferers showed the treatment to be a promising alternative to medication. The therapy is called transcranial magnetic stimulation, or TMS. Study findings were presented April 29, 2009 during the annual American Academy of Neurology scientific meeting in Seattle.

What Is Migraine? What Causes Migraines?
A migraine is a severe, painful headache that is often preceded or accompanied by sensory warning signs such as flashes of light, blind spots, tingling in the arms and legs, nausea, vomiting, and increased sensitivity to light and sound. The excruciating pain that migraines bring can last for hours or even days. Migraine headaches result from a combination of blood vessel enlargement and the release of chemicals from nerve fibers that coil around these blood vessels.

Targeting Glutamate Receptors For Migraine Prevention
When migraine strikes, because of severe pain, often accompanied by nausea and sensitivity to light and sound, sufferers are effectively disabled for up to 72 hours. Since they are forced to stop what they are doing until the pain and other symptoms subside, migraine causes a significant loss in productivity at work and the personal lives of those affected.

Safe Exercise For Migraine Sufferers
Many patients who suffer from migraines avoid taking aerobic exercise because they are afraid that the physical activity may bring on a serious migraine attack. Researchers at the Sahlgrenska Academy, University of Gothenburg, Sweden, have now developed an exercise programme that can improve fitness among migraine sufferers without aggravating this painful condition.

Valproate Anti-Epilepsy Drug In Pregnancy Linked To Lower IQ In Children
A study found that children born to women who took the anti-epilepsy drug valproate while pregnant tended to score significantly lower in IQ tests by an average of 6 to 9 points at age 3 than children born to mothers who took other anti-epilepsy drugs. The researchers said the findings support the recommendation that women of childbearing age should not be offered this drug as a first choice.

Exercise Reduces Migraine Suffering, Study Finds
While physical exercise has been shown to trigger migraine headaches among sufferers, a new study describes an exercise program that is well tolerated by patients. The findings show that the program decreased the frequency of headaches and improved quality of life. The study is published in Headache: The Journal of Head and Face Pain. The study used a sample of migraine sufferers who were examined before, during and after an aerobic exercise intervention.
   
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 Cancer News    

Work Status Changes More Common Among Women Receiving Chemotherapy For Breast Cancer, Study Says
Women with breast cancer who receive chemotherapy appear more likely than those treated with radiation therapy to experience a major change in work status, according to a study published in the journal Cancer, Reuters reports. For the study,

New Connection Between Cancer Cells, Stem Cells Pinpointed By Stanford Discovery
A molecule called telomerase, best known for enabling unlimited cell division of stem cells and cancer cells, has a surprising additional role in the expression of genes in an important stem cell regulatory pathway, say researchers at the Stanford University School of Medicine. The unexpected finding may lead to new anticancer therapies and a greater understanding of how adult and embryonic stem cells divide and specialize.

Lixte Biotechnology Holdings' Lead Compound, LB-1.2, Enhances The Effectiveness Of Standard Cancer Chemotherapy In Animal Models
Lixte Biotechnology Holdings (OTC Bulletin Board: LIXT) announced that investigators of the National Institute of Neurological Disorders and Stroke (NINDS) and the National Cancer Institute (NCI), National Institutes of Health and Lixte reported that its novel compound, LB-1.2, enhances the effectiveness of two standard chemotherapy drugs in mouse models of human cancers. This research is being conducted under a Cooperative Research and Development Agreement between NINDS and Lixte.

Updated Position Paper On Vegetarian Diets Released By The American Dietetic Association
The American Dietetic Association has released an updated position paper on vegetarian diets that concludes such diets, if well-planned, are healthful and nutritious for adults, infants, children and adolescents and can help prevent and treat chronic diseases including heart disease, cancer, obesity and diabetes.

Genetically Engineered Mice Yield Clues To 'Knocking Out' Cancer
Deleting two genes in mice responsible for repairing DNA strands damaged by oxidation leads to several types of tumors, providing additional evidence that such stress contributes to the development of cancer. That's the conclusion of a recent study* in DNA Repair by researchers at the National Institute of Standards and Technology (NIST), Oregon Health and Science University (OHSU) and the New York University School of Medicine (NYUSM).

2009 Dr. Paul Janssen Award For Biomedical Research Won By Axel Ullrich
Johnson & Johnson has announced that Axel Ullrich, Ph.D., director of the Department of Molecular Biology at the Max Planck Institute of Biochemistry in Germany, whose discoveries have led to novel cancer therapies including Herceptin® (trastuzumab) , is the winner of the 2009 Dr. Paul Janssen Award for Biomedical Research. An independent committee of world-renowned scientists selected Dr. Ullrich, who on September 8 will receive a $100,000 prize during a ceremony in Beerse, Belgium.

$500,000 Gruber Genetics Prize Awarded To Cancer Geneticist Janet Davison Rowley
Janet Davison Rowley, MD, a founder in the field of cancer cytogenetics and a renowned leader in molecular oncology, will receive the 2009 Genetics Prize of The Peter and Patricia Gruber Foundation. She is being honored with the prestigious international award for discoveries of recurrent chromosomal abnormalities in leukemias and lymphomas - discoveries that have revolutionized how cancer is understood and treated.

Gefitinib Receives European Licence For The Treatment Of Lung Cancer For Patients With EGFR Activating Mutation Positive Tumours
AstraZeneca announced that it has received a licence by the European Medicines Agency (EMEA) for its oral targeted anti-cancer drug, gefitinib, for EGFR (epidermal growth factor receptor-tyrosine kinase) activating mutation positive patients with Non Small Cell Lung Cancer (NSCLC). NSCLC is the most common type of lung cancer and accounts for 80% of all lung cancer cases.

New e-Science Service Could Accelerate Cancer Research
The University of Manchester and the European Molecular Biology Laboratory's European Bioinformatics Institute (EMBL-EBI) have launched a major new e-science resource for biologists which could accelerate research into treatments for H1N1 flu and cancer. Biocatalogue.

Cancer Survivors At Greater Risk Of Birth Complications; Special Monitoring Needed
Survivors of childhood cancer run particular risks when pregnant and should be closely monitored, the 25th annual conference of the European Society of Human Reproduction and Embryology heard today (Wednesday 1 July). Dr.

BMA Reaffirms Opposition To Assisted Suicide, UK
Doctors have reaffirmed their opposition to assisted suicide following a debate at the BMA's Annual Conference in Liverpool yesterday. Doctors rejected calls from Thameside doctor, Kailash Chand to change legislation to allow the choice of an assisted death by patients who are terminally ill and who have mental capacity.

Appeal For Cancer Patients To Trial New Nail Damage Remedy
The search is on for fifty cancer patients undergoing chemo or radiotherapy to trial an innovative, natural cosmetic product, Evonail, aimed at reversing the damage done to cracked or broken nails during anti-cancer treatments. Evolife's full range of support care products, including Evonail, are regularly used in France and in over 16 countries in the world, but they have only recently been launched in the UK through the

Pfizer Discontinues Phase 3 Trial Of Sutent(R) In Metastatic Colorectal Cancer
Pfizer Inc announced the discontinuation of the SUN 1122 Phase 3 trial that evaluated Sutent® (sunitinib malate) plus FOLFIRI (irinotecan plus infusional 5-fluorouracil and leucovorin) versus FOLFIRI alone for the first-line treatment of metastatic colorectal cancer (CRC).

Peregrine Awarded European Patent For Innovative Labeling Technology Featured In New Study In The Journal Of Nuclear Medicine
Peregrine Pharmaceuticals, Inc. (Nasdaq: PPHM) today announced that it has been awarded a European patent for a novel device and methods for linking biological agents to labels for diagnostic and therapeutic applications. The technology, which is known as In-Line labeling, was developed for the production of radiolabeled anti-cancer antibodies, but is applicable to other agents as well.

Advanced Prostate Cancer - New Review On PROSTVAC(TM) Published By Key Investigators From NCI
A just published Review in the publication "Expert Opinion on Investigational Drugs", Volume 18, Issue 7 2009, confirms the previous published information on PROSTVAC(TM). This is the most comprehensive and updated Review on PROSTVAC(TM) so far.

Colorectal Cancer - MDC Researchers Identify Genetic Markers For Metastasis Formation
Previously, only a few genes had been associated with the formation of metastases in colorectal cancer. Now, researchers of the Max Delbrück Center for Molecular Medicine (MDC) Berlin-Buch and Charité - University Medicine Berlin, Germany, have identified 115 genes that are disregulated both in the primary tumor and in its metastases. In the future, their findings may help identify patients with aggressive tumors at an earlier stage (Gastroenterology 2009, doi:10.1053/j.gastro.2009.

Damon Runyon Cancer Research Foundation Awards $2.7M To 7 Top Young Clinical Investigators
The Damon Runyon Cancer Research Foundation named 4 new Damon Runyon Clinical Investigators at its April 2009 Clinical Investigator Award Committee review. The recipients of this prestigious, three-year award are outstanding early career physician-scientists conducting patient-oriented cancer research at major research centers under the mentorship of the nation's leading scientists and clinicians. Each will receive $450,000 to support the development of his cancer research program.

Study Says High-Cost Cancer Drugs Have Little Benefit, Strain Health System
"Crunching data from published studies, the authors found that treating a lung-cancer patient with Erbitux, a drug that costs $80,000 for an 18-week regimen, prolongs survival by only 1.2 months," the Wall Street Journal reports.

Re-Do Your Family Barbeque: Experts Offers Tips On Grilling To Reduce Cancer Risks
Summer is in full swing, and barbeques are a perfect way to relax, spend time with family and friends, and celebrate the July 4th holiday. To help you better prepare for this popular activity, nutrition experts at The University of Texas M. D. Anderson Cancer Center offer advice on how to barbeque the healthy way. M. D. Anderson dietitian, Vicki Piper, R.D., L.D., encourages cookout fans to grill plenty of fruits and vegetables, and less meat.

Vegetarians Have Lower Cancer Risk, UK Study
A 12-year study that followed over 60,000 Britons, half of whom were vegetarian, suggests that vegetarians had a lower risk of developing cancer than meat-eaters. However, more studies are needed before we can use this evidence as sufficient reason to ask people to change their diets, say the researchers and other experts.

Extending The Shelf Life Of Antibody Drugs
A new computer model developed at MIT can help solve a problem that has plagued drug companies trying to develop promising new treatments made of antibodies: Such drugs have a relatively short shelf life because they tend to clump together, rendering them ineffective. Antibodies are the most rapidly growing class of human drugs, with the potential to treat cancer, arthritis and other chronic inflammatory and infectious diseases.

Sutent Significantly Improved Progression-Free Survival For Patients With Advanced Pancreatic Islet Cell Tumours
Pfizer announced preliminary results from a randomized Phase 3 trial of Sutent (sunitinib malate) in patients with advanced pancreatic islet cell tumours, also known as pancreatic neuroendocrine tumours, which is a different type of cancer than the more common pancreatic adenocarcinoma. Study findings demonstrated that median progression-free survival (PFS) was 11.1 months in patients treated with Sutent compared to 5.5 months in patients treated with placebo.

Hunt For Blood Test To Determine Melanoma Survival Rates
Research at the University of Leicester will be breaking new ground in the search for a simple blood test that could tell whether a patient with melanoma has the condition in an aggressive form. Melanoma is the most aggressive form of skin cancer. Staging, which involves determining the size of the tumour and its extent of spread, is the best predictor of whether a patient will succumb to disease or survive.

Studying The Anti-Cancer Capabilities Of A Special Purple Sweet Potato
A Kansas State University researcher is studying the potential health benefits of a specially bred purple sweet potato because its dominant purple color results in an increased amount of anti-cancer components. K-State's Soyoung Lim, doctoral student in human nutrition, Manhattan, is working with George Wang, associate professor of human nutrition at K-State, to understand the pigment effects of a Kansas-bred purple sweet potato on cancer prevention.

Gastrointestinal Endoscopy June Issue Study Highlights
Polyp detection rates at screening colonoscopy; EUS-based criteria for the diagnosis of chronic pancreatitis In the June issue of GIE: Gastrointestinal Endoscopy, the monthly peer-reviewed scientific journal of the American Society for Gastrointestinal Endoscopy (ASGE), a
   
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 Diabetes News    

Joint Replacement Patients With Diabetes Greatly Benefit From Controlled Glucose
Diabetics undergoing total joint replacement often are at a higher risk of experiencing complications after surgery due to various pre-existing health conditions. According to a new study published in the July 2009 issue of The Journal of Bone and Joint Surgery (JBJS), those complications are less likely to occur when a diabetic patient has glucose levels under control.

Interferon Alpha Can Delay Full Onset Of Type I Diabetes: UT Researcher
A low dose of oral interferon alpha shows promise in preserving beta cell function for patients with newly diagnosed type 1 diabetes, or juvenile diabetes, according to researchers at The University of Texas Medical School at Houston. The results of the Phase II trial are published in Diabetes Care, a journal of the American Diabetes Association.

Examining Dietary Influences Of Liver Disease
Diets high in protein and cholesterol are associated with a higher risk of hospitalization or death due to cirrhosis or liver cancer, while diets high in carbohydrates are associated with a lower risk. These findings are in the July issue of Hepatology, a journal published by John Wiley & Sons on behalf of the American Association for the Study of Liver Diseases (AASLD). The article is also available online at Wiley Interscience.

Treatment That Significantly Slows Progression Of Eye Damage In Persons With Type 1 Diabetes - University Of Minnesota
University of Minnesota Medical School researcher Michael Mauer, M.D., has found a treatment that significantly slows the progression of eye injury in people with type 1 diabetes, a common complication caused by this disease. By administering an antihypertensive, medication commonly prescribed to treat high blood pressure, Mauer and colleagues were able to slow progression of diabetic eye damage in more than 65 percent of participants involved in the study.

2009 Dr. Paul Janssen Award For Biomedical Research Won By Axel Ullrich
Johnson & Johnson has announced that Axel Ullrich, Ph.D., director of the Department of Molecular Biology at the Max Planck Institute of Biochemistry in Germany, whose discoveries have led to novel cancer therapies including Herceptin® (trastuzumab) , is the winner of the 2009 Dr. Paul Janssen Award for Biomedical Research. An independent committee of world-renowned scientists selected Dr. Ullrich, who on September 8 will receive a $100,000 prize during a ceremony in Beerse, Belgium.

Lap-Band Weight-Loss Surgery Can Reverse Metabolic Syndrome In Obese Teens
A new study of obese adolescents has shown that laparoscopic gastric banding surgery -- the "Lap-Band" procedure -- not only helps them achieve significant weight loss but can also improve and even reverse metabolic syndrome, reducing their risk for cardiovascular disease and diabetes.

Study Indicates Support Group Attendance Improves Post-Surgical Weight Loss
Major scientific contributors within the bariatric and psychiatric industries publicized the results of a recent study demonstrating that LAP-BAND(R) patients who regularly attend support groups experience considerably higher rates of post-surgical weight loss. Authors Dr. Kathryn A. Kaiser, Dr. Susan Franks and Dr. Adam Smith discussed their findings at the 26th Annual American Society for Metabolic & Bariatric Surgery (ASMBS) Meeting.

Shedding New Light On The Causes Of Polycystic Ovarian Syndrome And Its Effect On Brothers
Researchers have found evidence that chronic disease in either a mother or father can create unfavourable conditions in the womb that are associated with the development of polycystic ovarian syndrome (PCOS) in daughters. In another study, researchers found that brothers of women with PCOS and insulin resistance are themselves at greater risk of developing insulin resistance or diabetes, suggesting that factors associated with the condition can be passed down to sons as well as daughters.

Heatwave Advice For Diabetics
Experts are predicting record-breaking temperatures this week, so it's important to take precautions to ensure that your diabetes remains well-controlled in this extreme weather. Long periods of inactivity in the sun can affect diabetes control, making blood glucose levels higher than usual. On the flipside, insulin will be absorbed more quickly from the injection site in hot weather and this increases the risk of hypos.

Two Thirds Of People With Diabetes Not Receiving Vital Health Checks, UK
The latest National Diabetes Audit has revealed that 60 per cent of people with diabetes in England do not receive all of their vital annual health checks including blood glucose, blood pressure and eye tests.

Safe And Successful Fertility Treatment Possible In Women With Cystic Fibrosis
Women with cystic fibrosis can have fertility treatment to help them have babies without any long-term adverse effects on either themselves or their children, according to new research presented at the 25th annual meeting of the European Society of Human Reproduction and Embryology in Amsterdam. Until relatively recently, cystic fibrosis (CF) was a death sentence and most people with the disease died by the time they reached their teenage years.

PPD Confirms Takeda Receives FDA Complete Response For Alogliptin
PPD, Inc. (NASDAQ: PPDI) today announced that Takeda Pharmaceutical Company Limited issued a news release reporting that Takeda Global Research & Development Center, Inc., its wholly-owned U.S. subsidiary, has received a complete response letter from the U.S. Food and Drug Administration (FDA) regarding its new drug application (NDA) for alogliptin.

Roche Diabetes Care Announces Unique Coaching Program For Diabetes Educators As Part Of Long-Term Commitment To Fight The Disease
Roche, the maker of ACCU-CHEK blood glucose monitoring systems and insulin pumps, announced today the latest component of its Behavior Change through Patient Engagement (sm) program. Creative Coaching is an advanced educational program that fights the growing epidemic of diabetes by improving dialogue between diabetes educators and their patients.

Medical Experts Call For Greater Use Of Gastric Banding For Obese People With Type 2 Diabetes
UK experts are calling for greater consideration of gastric banding as an option for obese people with type 2 diabetes who need to lose weight. Dr Jonathan Pinkney, diabetologist, and Mr Paul Super, obesity surgeon, initiated this call to action following the recent European label change confirming that weight loss with Allergan's LAP-BAND [TM] AP System can lead to improvement or remission of type 2 diabetes.

Diabetes UK's Measure Up Roadshow Is A Success
Diabetes UK has so far encouraged more than 10,000 people in the UK to measure their waists and find out if they are at risk of developing Type 2 diabetes with its national Measure Up Roadshow which kicked off on June 3. The Measure Up Roadshow is touring the country until December in a bid to help people find out more about Type 2 diabetes and its risk factors.

Finding The Best Heart Disease And Stroke Treatments For Patients With Diabetes Using New Tool
Researchers from North Carolina State University and Mayo Clinic have developed a computer model that medical doctors can use to determine the best time to begin using statin therapy in diabetes patients to help prevent heart disease and stroke. "The research is significant because patients with diabetes are at high risk for cardiovascular disease and statins are the single most commonly used treatment for patients at risk of heart disease and/or stroke," says Dr.

European Medicines Agency Update On Safety Of Insulin Glargine
The European Medicines Agency (EMEA) is looking into four recently published registry studies investigating a possible relationship between insulin analogues, in particular insulin glargine, and the risk of cancer. The studies were published on the Diabetologia website on 26 June 2009.

Takeda Receives FDA Complete Response Letter For Alogliptin, An Investigational Treatment For Type 2 Diabetes
Takeda Pharmaceutical Company Limited ("Takeda") announced that Takeda Global Research & Development Center, Inc., a wholly owned United States (U.S.) subsidiary received on June 26 (U.S. time) a complete response letter from the U.S. Food and Drug Administration (FDA) regarding the Company's New Drug Application (NDA) for alogliptin, a selective dipeptidyl peptidase IV (DPP-4) inhibitor under investigation for the treatment of type 2 diabetes as an adjunct to diet and exercise.

AACE Response To Insulin Glargine Cancer Risk Articles In Diabetologia
On June 26, 2009 several articles published online in Diabetologia by the European Association for the Study of Diabetes investigated the possible relationship between use of insulin glargine (Lantus, sanofi-aventis) and the development of certain malignancies. The authors themselves, and the accompanying editorial, cautioned against over-interpretation of their limited data and analyses, which precluded them from drawing any firm conclusions.

Statement From The IDF Related To Studies Published In Diabetelogia Suggesting Possible Link Between Insulin Glargine And Cancer
The International Diabetes Federation (IDF) called for urgent assessment and responses from regulatory authorities into a possible link between the use of insulin glargine (an insulin analogue) and increased risk of cancer based on findings published on 26 June, 2009 in Diabetelogia, the journal of the European Association for the Study of Diabetes (EASD).

Donate Your Old Jewellery For A Good Cause, Diabetes UK
Diabetes UK is asking you to donate your unwanted or broken jewellery and accessories to our jewellery appeal. We will then convert your kind donations into crucial funds to support diabetes research projects. If you have an odd cufflink or earring, a watch that doesn't tick, a damaged necklace or a ring that doesn't fit, please send it to the address below.

Diabetes UK Reaches Twitter Milestone
Diabetes UK has just reached the 1,000 follower mark on Twitter, the social networking and micro-blogging site that allows its users to send and receive each other's updates, or 'tweets'. The charity, present on Twitter since October 2008, is finding that the service is proving to be an invaluable way of communicating directly with people with diabetes and of raising the awareness of the condition and its complications.

Hypoglycemia Increases Mortality Risk, Lengthens Hospital Stay For Diabetes Patients -- Even Outside The ICU
Diabetes patients who are hospitalized for non-critical illnesses, and develop hypoglycemia while hospitalized, are likely to remain hospitalized longer and face greater risk of mortality both during and after hospitalization, according to a study published in the July issue of Diabetes Care.

American Diabetes Association Related To Studies Published In Diabetelogia Suggesting Possible Link Between Insulin Glargine And Cancer
Diabetelogia, the journal of the European Association for the Study of Diabetes (EASD), published a series of research papers today examining a possible link between insulin glargine (brand name, Lantus) and cancer. Findings from these research papers are conflicting and inconclusive, and the American Diabetes Association cautions against over-reaction until more information is available.

Ohio May Face Medicaid Cuts And A Loss Of Coverage For Diabetics
In Ohio, a nursing home coalition warns of "life-threatening health risks" if Medicaid reimbursements are cut under Gov. Ted Strickland's proposed budget plan while diabetes patients in the state are threatened by a lack of coverage. The
   
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